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Searching information on drug research projects

This database contains information gathered in the course of the ERANID project during 2013 and 2014. Principally, it contains details of research projects on illicit drugs carried out since 2010 within the six ERANID countries and funded by the European Committee: Belgium; France; Italy; Portugal; The Netherlands; and the United Kingdom. However, this database will not capture all illicit drugs research carried out within a country.

90 projects matched the selected criteria:

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ESCAPAD 2011 (National survey on Health and drug use carried out during the Day of defense preparation)

Funding country
France
Project starting year
2011
Project ending year
2012
Area(s) of research
Prevalence, incidence and patterns of drug use, Determinants of drug use, Consequences of drug use
Objectives
To assess the attitudes and behaviors of the young people at the end of adolescence, related to their psychoactive substance uses and patterns of uses, as well as their health and lifestyles. To measure the evolutions of these behaviours and lifestyles in the course of time To carry out comparisons with the school surveys (ESPAD and HBSC) and the National Health Barometer Survey in adult general population aged 18-75 years.
Scientific discipline(s) involved
History, Sociology
Read more…
Objectives (native)
- To assess the attitudes and behaviors of the young people at the end of adolescence, related to their psychoactive substance uses and patterns of uses, as well as their health and lifestyles. - To measure the evolutions of these behaviours and lifestyles in the course of time - To carry out comparisons with the school surveys (ESPAD and HBSC) and the National Health Barometer Survey in adult general population aged 18-75 years.
Initial identified needs
The end of the compulsory national military service has lead the French Health service of Armies (SA) to cease the annual epidemiological follow-up on addictive behaviours, in 1996. This interruption deprived the information system on drugs and drug-addiction of a valuable monitoring system centred on a population (male, young people) very concerned and particularly reactive to the recent trends. This is why, under the impetus of the French Observatory of Drugs and Drug-addiction (OFDT) and the Interdepartmental Mission for the Fight against Drug and Drug-addiction (MILDT), the of the Partnership Liaison Mission within the Ministry of Defence has agreed to set up the ESCAPAD survey, from 2000 and every 3 years onwards, towards boys and girls (aged 17-18) convened for the Day of Call and Preparation to Defense (JAPD).
Performed by
OFDT (French Monitoring Centre on Drugs and Drug Addictions)-General Population Survey Unit
INSERM (French National Institute of Health and Medical Research)
Funded by
French Monitoring Centre on Drugs and Drug Addictions
Summary references
http://www.ofdt.fr/BDD_len/Bd_stats/4_Doc.xhtml (in French only)
Website
http://www.ofdt.fr/ofdtdev/live/donneesnat/escapad.html
Published reference(s)
SPILKA, S., LE NÉZET, O. & TOVAR, M. L. (2012) Les drogues à 17 ans : premiers résultats de l'enquête ESCAPAD 2011. Tendances, 1-4. LEGLEYE, S., BECK, F., KHLAT, M., PERETTI-WATEL, P. & N., C. (2012) The influence of socioeconomic status on cannabis use among French adolescents. J Adolesc Health, 50(4), 395-402. LEGLEYE, S., BECK, F., KHLAT, M., PERETTI-WATEL, P. & N., C. (2012) The influence of socioeconomic status on cannabis use among French adolescents. J Adolesc Health, 50(4), 395-402. LEGLEYE, S., JANSSEN, E., BECK, F., CHAU, N. & KHLAT, M. (2011) Social gradient in initiation and transition to daily use of tobacco and cannabis during adolescence: a retrospective cohort study. Addiction, 106, 1520-1531. LEGLEYE, S., OBRADOVIC, I., JANSSEN, E., SPILKA, S., LE NEZET, O. & BECK, F. (2010a) Influence of cannabis use trajectories, grade repetition and family background on the school-dropout rate at the age of 17 years in France. European Journal of Public Health, 20, 157-163. LEGLEYE, S., SPILKA, S., LE NÉZET, O. & LAFFITEAU, C. (2010b) Drug use among 17-year-olds. Results of the 2008 ESCAPAD survey. Tendances, 1-6 SPILKA, S., BECK F., LEGLEYE S. (2010) Alcool, tabac, cannabis : les drogues à 17 ans (synthèse). Agora débats/jeunesses (Jeunes & santé : entre actions publiques et comportements individuels), (54), 125-130. LEGLEYE, S., SPILKA, S., LE NÉZET, O. & LAFFITEAU, C. (2010) Drug use among 17-year-olds. Results of the 2008 ESCAPAD survey. Tendances, 1-6. http://www.ofdt.fr/BDD/publications/docs/eftaslp6.pdf
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ESM: Factors associated to craving and drug use in patient who were addicted when starting a treatment. A study based on every day life.

ESM : Facteurs associés au craving et à la consommation chez des sujets dépendants aux substances en début de prise en charge. Une étude en vie quotidienne.
Funding country
France
Project starting year
2009
Project ending year
2012
Area(s) of research
Determinants of drug use
Objectives
To dertermine the factors influencing craving
Scientific discipline(s) involved
History, Neurosciences, Psychology, Other medical sciences
Read more…
Objectives (native)
Déterminer les facteurs influençant le craving
Initial identified needs
Understanding of the determining factors of craving
Initial identified needs (native)
Compréhension des déterminants du craving
Performed by
Phénoménologie et déterminants des comportements appétitifs, addictologie et psychiatrie / Sanpsy CNRS USR 3413
CNRS UMR 5231
Funded by
Conseil régional d'Aquitaine, CNRS
Summary references
Serre F, Fatseas M, Debrabant R, Alexandre JM, Auriacombe M, Swendsen J. Ecological momentary assessment in alcohol, tobacco, cannabis and opiate dependence: A comparison of feasibility and validity. Drug Alcohol Depend 2012;126:118–123
Website
Published reference(s)
Serre F, Fatseas M, Debrabant R, Alexandre JM, Auriacombe M, Swendsen J. Ecological momentary assessment in alcohol, tobacco, cannabis and opiate dependence: A comparison of feasibility and validity. Drug Alcohol Depend 2012;126:118–123
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ESPAD (European School Survey Project on Alcohol and other Drugs) in France in 2011

Funding country
France
Project starting year
2011
Project ending year
2012
Area(s) of research
Prevalence, incidence and patterns of drug use, Determinants of drug use, Consequences of drug use
Objectives
To assess the attitudes, use behaviours and opinions of the French middle-schoolers in respect to psychoactive substances (particularly alcohol and illicit drugs) and in relation with their health and lifestyles. To measure the evolutions of these behaviours and lifestyles over time To make international comparisons
Scientific discipline(s) involved
History, Sociology
Read more…
Objectives (native)
- To assess the attitudes, use behaviours and opinions of the French middle-schoolers in respect to psychoactive substances (particularly alcohol and illicit drugs) and in relation with their health and lifestyles. - To measure the evolutions of these behaviours and lifestyles over time - To make international comparisons
Initial identified needs
At the end of the years 1980, the Group Pompidou (Council of Europe) sets up, at the European level, a think tank in order to improve the epidemiological data collection on drug uses among the young Europeans. In 1995, the coordination of the first ESPAD survey is entrusted to the Swedish Council of Information on Alcohol and other drugs (CAN) to fill the gap in comparable data in respect to the drug uses within the young European population. For pragmatic reasons it was decided to conduct the survey among 15–16 year old students in classrooms. France joins the survey at its second edition, in 1999, under the impetus of the French National Institute of Health and Medical Research (INSERM) Inserm and with the financial support of the French Monitoring Centre on Drugs and Drug Addictions (OFDT). Since 2007, the survey has been carried out by the OFDT which ensures both funding and coordination.
Performed by
OFDT (French Monitoring Centre on Drugs and Drug Addictions)-General Population Survey Unit
INSERM (French National Institute of Health and Medical Research)
Funded by
OFDT (French Monitoring Centre on Drugs and Drug Addictions), CAN (Swedish Council for Information on Alcohol and Other Drugs)
Summary references
http://www.ofdt.fr/ofdtdev/live/donneesnat/espad.htmlhttp://espad.org/
Website
The General ESPAD project is accessible at: http://espad.org/
Published reference(s)
- Spilka S. et Le Nézet O., « Premiers résultats du volet français de l’enquête European School survey Project on Alcohol and other drugs (ESPAD) 2011 », Note de synthèse, mai 2012, 17 p. - HIBELL, B., GUTTORMSSON, U., AHLSTRÖM, S., BALAKIREVA, O., BJARNASON, T., KOKKEVI, A. & KRAUS, L. (2012) The 2011 ESPAD report - Substance use among students in 36 European countries. Stockholm, CAN (The Swedish Council for Information on Alcohol and other Drugs).
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Evaluation of awareness-building training courses on the drug related harms

Funding country
France
Project starting year
2010
Project ending year
2012
Area(s) of research
Prevention responses, Law enforcement responses, Consequences of drug use
Objectives
To characterize the sociodemographic and penal structure of both drug users sentenced to a awareness-building training courses on the drug related harms and those actually received in training course, To assess the adequacy of the reached publics compared to the targeted population. To describe the supplied training courses, more particularly with regard to their conditions of implementation and the possible difficulties occurred. To assess the beneficiaries’ perception of the training courses and its immediate effects, in order to pave the way for reflection on relevant adjustments to the target public’s needs.
Scientific discipline(s) involved
History
Read more…
Objectives (native)
- to characterize the sociodemographic and penal structure of both drug users sentenced to a awareness-building training courses on the drug related harms and those actually received in training course, - to assess the adequacy of the reached publics compared to the targeted population. - to describe the supplied training courses, more particularly with regard to their conditions of implementation and the possible difficulties occurred. - to assess the beneficiaries’ perception of the training courses and its immediate effects, in order to pave the way for reflection on relevant adjustments to the target public’s needs.
Initial identified needs
Since 2007, people (aged thirteen and over) arrested for detention and use of narcotics can be sentenced to carry out a “awareness-building training courses on the drug related harms”. This alternative to prosecution is payable by contravener and has an educational purpose. It addresses the occasional drug users (then non addicted), which must be dissuaded from renewing drug taking, making them aware of the consequences of drug use. These training courses have been conceived to offer to public prosecutors an alternative to legal reminders, considered to be insufficiently dissuasive. They must allow systemising and accelerating the penal response to the narcotic uses, in particular for at the onset of use, by developing new educational sanction. In this aim, the legislator has decreed a broad scope of applicability and particularly flexible conditions of implementation. In 2010, this new kind of criminal response was still poorly measured through the ordinary statistical information system. Therefore, 3 years and half after the law of March 5th, 2007 which founds the awareness-building training courses, the Ministry of Justice (Criminal Matters and Pardons Directorate (DACG)) appointed the French Monitoring Centre on Drugs and Drug Addiction (OFDT) to assess their development of and the conditions of their implementation.
Performed by
OFDT (French Monitoring Centre on Drugs and Drug Addictions) - Unit of Public Policies Evaluation
Funded by
OFDT (French Monitoring Centre on Drugs and Drug Addictions), Ministry of Justice
Summary references
Website
Published reference(s)
OBRADOVIC, I. (2012a) Évaluation des stages de sensibilisation aux dangers de l'usage de stupéfiants. Saint-Denis, OFDT. OBRADOVIC, I. (2012b) Les stages de sensibilisation aux dangers de l'usage de produits stupéfiants. Évaluation de la mise en oeuvre du dispositif quatre ans après sa création. Tendances, 1-6. OBRADOVIC, I. (2010) The criminalization of drug use in France. Tendances, 1-6.
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Foreign experiences of infectious risk reduction in prison settings

Funding country
France
Project starting year
2012
Project ending year
2012
Area(s) of research
Law enforcement responses, Harm reduction responses
Objectives
To identify the experiences of opiate substitution treatments (OST) and Syringe exchange programmes (SEP) delivered in prisons, at the international level (including experimental projects). To describe the context of implementation of these experiences, the intervention patterns and the providers’ practices and the main conclusions.
Scientific discipline(s) involved
Other discipline
Read more…
Objectives (native)
- to identify the experiences of opiate substitution treatments (OST) and Syringe exchange programmes (SEP) delivered in prisons, at the international level (including experimental projects). - to describe the context of implementation of these experiences, the intervention patterns and the providers’ practices and the main conclusions.
Initial identified needs
Confinement is frequently part of the injector drug users’ trajectory: the part of the intravenous drug users (IVDU) having already been imprisoned varies between 56 % and 90 % (Ball, on 1995; Norman and al ., on 1995; Beyrer and al ., on 2003), vs 43 % a 61 % in France. In most of countries, an important proportion of prisoners declare they have an intravenous drug use: between 10 % and 48 % male inmates and between 30 % and 60 % females (Fazel and al., on 2006). These IVDU are not only current users, who pursue in prison their consumption initiated outside (Lukasiewicz and al., on 2007) but also the ones who have begun using drug while in detention, in particular as a consequence of difficulties connected to the prison regime and prison life violence (Hughes, Huby, on 2000), in a context of chronic overpopulation in many countries. The prevalences of the HIV and the viral hepatitis are higher among the prison population. Even though most of the HIV infected inmates have contracted the virus before being imprisoned, confinement also constitutes a period at risk (Dolan, Wodak, on 1999; MacDonald, on 2005). The risk of contamination in prison is all the more prevalent since sharing practices of the injection material are commonplace. These facts stress out the need of effective and adapted policies aimed at reducing the infectious risk in prison settings.
Performed by
OFDT (French Monitoring Centre on Drugs and Drug Addictions) - Unit of Public Policies Evaluation
Funded by
OFDT (French Monitoring Centre on Drugs and Drug Addictions)
Summary references
Website
Published reference(s)
OBRADOVIC, I. (2012c) Réduction des risques en milieu pénitentiaire. Revue des expériences étrangères. Note n°2012-04, à l'attention de la MILDT. Saint-Denis, OFDT.
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Gender and addictions

Genre et addictions
Funding country
France
Project starting year
2008
Project ending year
2012
Area(s) of research
Prevalence, incidence and patterns of drug use, Prevention responses, Determinants of drug use
Objectives
Décrire et interpréter les différence de genre dans les pratiques addictives
Scientific discipline(s) involved
History, Sociology, Other discipline
Read more…
Initial identified needs
Need of gender-specific selective prevention
Initial identified needs (native)
Besoin en prévention ciblée selon le genre
Performed by
CNRS - CMH
INPES
CERMES 3
INED
Funded by
INPES
Summary references
http://www.ncbi.nlm.nih.gov/pubmed/20132782
Website
http://www.ncbi.nlm.nih.gov/pubmed/20132782
Published reference(s)
Beck F., Maillochon F., 2012, Genre, santé et soins, in Bimes-Arbus S, Czernichow P, Simeoni M-C, Carricaburu D, Dartigues J-F, Le Coz P, Le Faou A-L, Metzger M-H, E 7 - Santé - Société - Humanité (cours), Pass’Santé, Elsevier/Masson, Paris, 559-567. Beck F., Legleye S., Maillochon F., de Peretti G., 2010, Femmes influentes sous influence ? Genre, milieu social et usages de substances psychoactives Médecine/science, 26(1), 95-97. Beck F., Legleye S., Maillochon F., de Peretti G., 2009, La question du genre dans l’analyse des pratiques addictives à travers le Baromètre santé, France 2005, BEH, n°10-11, 90-93. Beck F., Legleye S., Maillochon F., de Peretti G., 2008, Le rôle du milieu social dans les usages de substances psychoactives des hommes et des femmes, Regards sur la Parité, INSEE, pp. 65-82. disponible sur : http://www.insee.fr Legleye S., Beck F., Maillochon F., de Peretti G., Usages de drogues en France parmi les hommes et les femmes : une question de milieu social ? Congrès international d’épidémiologie de l’ADELF (Association des Epidémiologistes de Langue Française) et d’EPITER (Association pour le Développement de l’Epidémiologie de Terrain) 10-12 septembre 2008. Legleye S., Beck F., Maillochon F., de Peretti G., Gender differences in drug use in France : a Matter of social status ? 38th world congress ot the International Institute of Sociology, Budapest, June 27-29, 2008 Beck F., Legleye S., Maillochon F., de Peretti G. « Inégalités sociales et santé des femmes », 2ème journée de réflexion de l’Association Nationale de Prévention en Alcoologie et Addictologie (ANPAA), 7 mars 2008, Lille.
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Methaville

Methaville
Funding country
France
Project starting year
2009
Project ending year
2012
Area(s) of research
Prevalence, incidence and patterns of drug use, Prevention responses, Treatment responses
Objectives
To demonstrate that after one year of treatment, the proportion of opioid users among patients under substitution treatment is not lower among patients followed by general practionners than among patients followed in specialised drug treatment centres (CSAPA).
Scientific discipline(s) involved
History, Psychology, Pharmacology, Other discipline
Read more…
Objectives (native)
montrer la non infériorité de la proportion de consommateurs d'opioids après un an de traitement des patients ayant initié en ville par rapport aux patients ayant initié en centre de soins (csapa)
Initial identified needs
To increase access to methadone through GPs
Initial identified needs (native)
augmenter l'accès à la méthadone grâce à le médecine de ville
Performed by
INSERM U912 (French National institute for health and medical research)
Funded by
ANRS, DGS
Summary references
http://www.biomedcentral.com/1471-2458/12/488
Website
http://www.biomedcentral.com/1471-2458/12/488
Published reference(s)
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RELIONPREDIL-Experimental survey for the monitoring of prevention actions related to illicit or licit drugs

Funding country
France
Project starting year
2010
Project ending year
2012
Area(s) of research
Prevention responses
Objectives
To characterise the targets, diffusion, method and resources ( theoretical and practical components) of local prevention actions in the main concerned setting. To pave the way for a national complete system covering the main concerned sectors (such as educational, occupational, community judicial settings), whatever the funding sources of the actions (whether specifically subsidized or absorbed in the deliverer’s personal costs and overheads). To follow-up possible changes in the prevention practices
Scientific discipline(s) involved
History
Read more…
Objectives (native)
- to characterise the targets, diffusion, method and resources ( theoretical and practical components) of local prevention actions in the main concerned setting. - to pave the way for a national complete system covering the main concerned sectors (such as educational, occupational, community judicial settings), whatever the funding sources of the actions (whether the costs are covered by specific subsidises or by the deliverer’s personal costs and overheads). - to follow-up possible changes in the prevention practices
Initial identified needs
Since 2006, the OFDT has tried to palliate the longstanding lack of information on the implemented prevention actions in France, by progressively setting-up a national observation system for universal or selective prevention practices related to both legal and illegal drugs. This experimental survey, entitled RELIONPREDIL (Survey for the monitoring of prevention actions related to illicit or licit drugs) has been based on three phases of local experimentation, the last one in 2011. Its design has been adjusted after each step in respect to the methodology of data collection and the available resources.
Performed by
OFDT (French Monitoring Centre on Drugs and Drug Addictions) - Unit of Public Policies Evaluation
Funded by
OFDT (French Monitoring Centre on Drugs and Drug Addictions)
Summary references
Website
Published reference(s)
MUTATAYI, C. (2012) RELIONPREDIL 2011. Actions de prévention des usages de drogues illicites et licites en Rhône-Alpes. Saint-Denis, OFDT.
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Respiratory effects of drugs of abuse

Effets respiratoires des substances donnant lieu à abus
Funding country
France
Project starting year
2008
Project ending year
2012
Area(s) of research
Mechanism of drug use and effects
Objectives
To describe the respiratory mechanisms to better understand and treat the intoxicated fellows.
Scientific discipline(s) involved
Other medical sciences, Other discipline, Toxicology
Read more…
Objectives (native)
Décrire les mécanismes respiratoires afin de mieux comprendre et prendre en charge les intoxiqués
Initial identified needs
Need to identify the mechanisms of the respiratory effects of substances of abuse (THC, GHB, ethanol) and specially their toxic effects
Initial identified needs (native)
Besoin de préciser les mécanismes des effets respiratoires de substances donnant lieu à abus (THC, GHB, éthanol) et plus particulièrement de leurs effets toxiques
Performed by
INSERM U705 Neuropharmacologie des addictions (French National institute for health and medical research)
Institut de recherche criminelle de la gendarmerie nationale
Funded by
INSERM U705, IRCGN
Summary references
http://www.theses.fr/2012PA05P628
Website
Non
Published reference(s)
http://www.ata-journal.org/articles/ata/abs/2012/04/ata120017/ata120017.html
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Analyses of patients treated by methadone and buprenorphine for more than 8 years

Analyses de patients traités par méthadone et buprénorphine depuis plus de 8 ans
Funding country
France
Project starting year
2011
Project ending year
2013
Area(s) of research
Prevalence, incidence and patterns of drug use, Treatment responses, Determinants of drug use, Consequences of drug use, Mechanism of drug use and effects
Objectives
To describe the future of people undertook a treatment based either on methadone or buprenorphine, 8 years ago or more
Scientific discipline(s) involved
History, Neurosciences, Psychology, Other medical sciences, Addictology
Read more…
Objectives (native)
Décrire le devenir de personnes ayant débuté un traitement par méthadone ou buprénorphine il y a 8 ans ou plus
Initial identified needs
need of better knowing the long-term effects of treatments based on methadone or buprenorphine
Initial identified needs (native)
Mieux connaitre les effets au long cours des traitements par méthadone et buprénorphine
Performed by
Phénoménologie et déterminants des comportements appétitifs, addictologie et psychiatrie / Sanpsy CNRS USR 3413
Pôle Addictologie, CH Charles Perrens, Bordeaux, France
Bizia, CH Côte Basques, Bayonne, France
Funded by
RB Pharmaceutical
Summary references
M. Auriacombe, C. Denis, V. Beltran, J-M. Alexandre, R. Debrabant, F. Serre, J-P. Daulouede, M. Fatseas. Ten-year outcome of patients in methadone and buprenorphine maintenance treatment in outpatient settings. San Diego, CA, June 2013. (College on Problems of Drug Dependence) CPDD 75th Annual Meeting Abstract Book page 6. www.cpdd.org
Website
Published reference(s)
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